QuantaTrace Ltd is a UK-based deep-tech company developing advanced authentication technologies for regulated and high-risk supply chains, with an initial focus on pharmaceuticals. The company’s core technical capability is the use of quantum dot–based physical unclonable functions (PUFs), where intrinsic nanoscale variability in semiconductor nanomaterials is exploited to generate unique, non-replicable optical signatures. These signatures are read using controlled photonic excitation and captured via optical sensing, enabling robust physical authentication rather than reliance on purely digital identifiers. QuantaTrace integrates nanomaterials synthesis, optical characterisation, and secure verification workflows, supported by machine-learning–assisted pattern recognition to improve robustness against noise, ageing, and measurement variability. The approach is designed to be compatible with existing track-and-trace infrastructures and regulatory frameworks, augmenting conventional serialisation with a physically bound security layer. The company is building a protected IP portfolio spanning material formulation, optical response capture, and authentication methods, positioning it at the intersection of quantum materials, photonics, and secure sensing.